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Technical Development Scientist

South San Francisco, CA 94080

Posted: 05/14/2024 Employment Type: Contract Industry: Research and Discovery Job Number: 11706 Pay Rate: $48.00 - $62.00 Remote Friendly: Onsite

Job Description

Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.  They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.

Job Overview:

RMG, in the Cell Culture and Bioprocess Operations department, is responsible for providing support to pre-Early Stage Research to Early Development projects with high-throughput protein production from mammalian transient cultures. We are looking for a motivated candidate with cell culture and sterile technique experience to join our team to enable protein production and help advance our portfolio.

Key Responsibilities:
  • Perform transient transfections in CHO and HEK293 cells in scales 1mL to 25L to support pipeline productions adhering to established protocols.
  • Maintain seed train cell cultures in bioreactors and shake flasks.
  • Operate liquid handlers - Tecan and Hamilton for automated processes.
  • Operate wave bag reactors for productions and cell maintenance
  • Maintain and troubleshoot key cell culture instruments such as Vi-Cell, Nova Flex2, Nova Flex, Cedex and bioreactors.
  • Participate in troubleshooting production or platform processes.
  • Participate in lab management and data management.
  • Contribute to improving existing cell culture platforms and developing new platforms to deliver diverse protein and cellular reagents to enable a large number of research programs.
  • The candidate must be highly self-motivated, organized, detail oriented and responsive to feedback.
  • The candidate is expected to precisely follow written procedures, practice sterile technique, demonstrate accurate documentation skills, and report deviations in a timely manner.
  • They should be able to work independently within guidelines and policies, with minimal guidance.

Job Requirements

  • Required:
    • PhD (with 0-2yrs relevant experience) in Biotechnology, Chemistry, Biochemistry or related fields.
    • Suspension adapted mammalian cell culture (CHO and/or HEK293)
    • Excellent written and verbal communication skills, and have strong collaborative skills.
  • Preferred:
    • State-of-the-art transient and stable protein expression experience
    • Relevant bioreactor experience
    • Hands-on experience with automation and liquid handlers like Tecan Freedom Evo and Hamilton Microlab Star.
    • Knowledge of cell biology, cell engineering, molecular biology, recombinant protein purification and protein characterization is preferred.

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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