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Technical Development Scientist

South San Francisco, CA 94080

Posted: 11/16/2023 Employment Type: Contract Industry: Research and Discovery Job Number: 11483 Pay Rate: $75.00 - $99.00 Remote Friendly:

Job Description

Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions.  They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.

Job Overview:
This position is part of the Small-Molecule Impurities Group in the Protein Analytical Chemistry department responsible for analyzing and managing small-molecule impurities to support process development and validation activities. This group utilizes advanced analytical tools such as NMR, GC-MS, LC-MS, and ICP-MS to quantify process-related small-molecule impurities, identify unknown compounds of interest, investigate product quality issues, and conduct extractables and leachables (E&L) studies.  In this role, you will perform both wet chemistry and instrumental analysis to support the SMIG projects in a timely manner.  You will be exposed to various aspects of small-molecule analysis in complex biological matrices.

Responsibilities:
  • Process protein drug samples for instrumental analysis using extraction techniques such as liquid-liquid extraction; prepare standards and replicates; spike analytes.
  • Run samples on LC-MS and/or GC-MS using existing methods or develop/optimize new methods; perform method validation following a protocol.
  • Analyze data to quantify analytes and/or identify unknown compounds.
  • Document results properly and author reports; communicate results to project teams.
  • Help with building and maintaining an internal E&L database and library.

Job Requirements

Basic Qualifications:
  • B.S./B.A. degree in chemistry, materials science or a relevant scientific discipline with 3+ years of experience.
  • Good understanding of chromatography and mass spectrometry with 2+ years of hands-on experience.
  • Demonstrated capability of performing wet chemistry procedures such as solution preparation, sample processing, and quantitative analysis.
  • Strong troubleshooting and problem-solving ability.
Preferred Qualifications:
  • An advanced degree (M.S.) in analytical chemistry.
  • Experience with E&L analysis or trace analysis.
  • Hands-on experience with protein sample preparation, high-resolution mass spectrometry (HRMS) or analytical method development and validation using LC-MS or GC-MS.
  • Organization and documentation skills in a regulated environment.

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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About South San Francisco, CA

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