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Sr. Research Associate/Associate Scientist, Disease Modeling

South San Francisco, CA 94080

Posted: 04/27/2023 Employment Type: Direct Hire Industry: Scientific Job Number: 11159 Pay Rate: $100K - $120K

Job Description


Job Summary

The Sr. Research Associate/Associate Scientist, disease modeling, is responsible for developing and executing novel cellular protocols and assisting in vivo disease modeling efforts within Therapeutic Team. This individual will perform cell line engineering and build an extensive repertoire of scalable cellular and in vivo models for multiple disease indications. This position includes technically diverse bench work and the training of research staff in techniques and equipment used to support drug validation.

What you will accomplish
  • Cell line engineering
  • Design and perform in vitro and in vivo experiments for disease modeling
  • Support the development of assay strategies and work across functions in experimental design, troubleshooting, sample analysis, data interpretation, and report generation
  • Perform assays such as but not limited to FACS, flow cytometry, ELISA, RT-qPCR, and ddPCR
  • Develop, author, and maintain SOPs/ELN
  • Support iPSC culturing and differentiation as needed

Qualifications
  • BS in related discipline + >5 years or MS in related discipline+ >3 years experience, in an academic or biotech, biopharma, pharmaceutical industry.

Technical Requirements and Skills:

Proficient working knowledge and experience in any of the following:
  • In depth of research experience in cell and molecular biology and assay development
  • Experience with cell line engineering (using CRISPR)
  • Strong skills in molecular biology (including DNA and RNA extraction, PCR, and qPCR)
  • Familiar with molecular cloning, gene engineering, and seamless cloning
  • Technical experience with primary cell culture and cell culture of immortalized cell lines and stem cells
  • Both 2D and 3D (organoid) cell culture and assay experience
  • Experience in characterizing cellular phenotype via multi-color flow cytometry, transcriptomics, or high-content imaging
  • Experience with lab automation for the cell-based screening assay and sample preparation

Job Requirements

 
Qualifications
  • BS in related discipline + >5 years or MS in related discipline+ >3 years experience, in an academic or biotech, biopharma, pharmaceutical industry.

Technical Requirements and Skills:

Proficient working knowledge and experience in any of the following:
  • In depth of research experience in cell and molecular biology and assay development
  • Experience with cell line engineering (using CRISPR)
  • Strong skills in molecular biology (including DNA and RNA extraction, PCR, and qPCR)
  • Familiar with molecular cloning, gene engineering, and seamless cloning
  • Technical experience with primary cell culture and cell culture of immortalized cell lines and stem cells
  • Both 2D and 3D (organoid) cell culture and assay experience
  • Experience in characterizing cellular phenotype via multi-color flow cytometry, transcriptomics, or high-content imaging
  • Experience with lab automation for the cell-based screening assay and sample preparation

Meet Your Recruiter

Lexie Pierce
Recruiter

As a Compass recruiter, Lexie brings in 15 years of experience in leadership and employee growth and development. She's incredibly passionate about helping candidates find and accept new opportunities, ultimately leading her to start her recruiting career in the life science industry. Her favorite part about connecting with Compass candidates and clients is witnessing the excitement the candidates exude and making an impact on their lives.

 

Outside of the office, Lexie enjoys going to the farmers' market on Saturdays with her son so she can find the best produce to use in her family dinners. She enjoys cooking, reading, knitting, restoring furniture, and spending time with her family and friends. Lexie is also passionate about supporting organizations that are looking to educate the community about Congenital Heart Defects (CHD).

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