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Senior Research Associate/Associate Scientist, Process Development (Downstream)

South San Francisco, CA 94080

Posted: 03/23/2023 Employment Type: Direct Hire Industry: Research and Discovery Job Number: 10886 Pay Rate: $100k to $120k

Job Description

Our client is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation.


  • This individual will be a key member of the Process Development team, performing primarily downstream process optimization activities for AAV based production platform.
  • Support development of a suspension cell AAV production platform in-house.
  • Conduct studies to enable development of representative scale down models for manufacturing processes.
  • Design and conduct experiments to assess critical and key process parameters and process controls and study their impact on critical quality attributes for AAV production.
  • Analyzing and interpreting experimental results; suggesting changes or additional experiments to improve the robustness and/or reproducibility of the production process.
  • Conduct dPCR and flow cytometry experiments and analysis.
  • Thorough documentation of experimental data and analysis
  • Sample inventory maintenance.

Job Requirements

  • Experience using DOE software to design experiments a key plus
  • Meticulous attention to detail and demonstrated experience of carefully recording methods and results.
  • Proven and consistent work ethic. Self-directed; open to challenges with enthusiasm.
  • A strong aptitude to learn and take on new challenges.
  • Outstanding collaboration, problem solving team player with excellent communication and organizational skills.
  • Experience in mammalian cell culture (both adherent and suspension), aseptic techniques, transfections and analytical techniques such as PCR and flow cytometry
  • Prior experience working in a fast-paced, start-up environment.


  • BS degree in Cell Biology, Biochemistry, Biology or a related discipline plus a minimum of 3-4 years of experience as a research associate within a biotech or pharmaceutical company.

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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