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Scientist II

South San Francisco, CA 94080

Posted: 03/17/2026 Employment Type: Contract Industry: Research and Discovery Job Number: 12562 Pay Rate: $47.00 - $52.00 Remote Friendly: Onsite

Job Description

Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.
 
Overview:

The Bioconjugation and Delivery group in the Protein Sciences organization is responsible for the design and generation of new therapeutic modalities that combine the engineering and analytical principles of multiple scientific disciplines. We are excited to be at the forefront of therapeutic design by generating molecules with unique mechanisms of action. We are seeking a talented early-in-career Scientist to join our team to advance our mission by learning and applying advanced bioconjugation techniques with precise analytical characterization. This position offers hands-on experience in drug development, including protein bioconjugation. This position is located in South San Francisco and is an on-site laboratory research position.

Key Responsibilities:
  • Bioconjugation of proteins utilizing chemical and/or enzymatic conjugation methods, including reaction design and optimization.
  • Development, optimization, and implementation of purification protocols of bioconjugates using common protein purification techniques.
  • Analytical characterization of reaction mixtures and purified conjugates employing chromatographic techniques (e.g. SEC, HIC, IEX), SDS-PAGE, colorimetric assays, as well as 1D and 2D mass spectrometry.
  • Data reporting, interpretation of results, and data presentation to internal teams.
  • Sample management of completed conjugates and related starting materials using internal inventory systems.
  • Collaboration with scientists from multiple functional and therapeutic areas to advance molecules through the drug discovery pipeline.

Job Requirements

Required Education:
  • Must have attained a Bachelor's Degree or higher in Chemistry, biochemistry, chemical biology, biophysics, biology, biomedical engineering, or related fields.

Required skills:
  • Basic understanding of protein purification and analytical techniques.
  • Previous experience with FPLC, HPLC or LCMS.
  • Excellent communication, collaboration, and interpersonal skills.

Other Preferred Qualifications:
  • Previous experience with oligonucleotides and/or antibody oligonucleotide generation

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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About South San Francisco, CA

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