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SD_Scientist I

San Diego, CA 92111

Posted: 06/05/2026 Employment Type: Contract Industry: Research and Discovery Job Number: 12661 Pay Rate: $28.00 - $45.00 Remote Friendly: Onsite

Job Description

Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.

Position Summary:

The Scientist I will be a vital contributor to our non-viral cell and gene therapy delivery platform, primarily focused on R&D for innovative nucleic acid payload technologies. This role involves evaluating novel mRNA and DNA designs using a range of molecular biology techniques, including plasmid cloning, in vitro validation, and the production of in vitro-transcribed mRNA. To verify successful expression, the scientist will utilize assays such as Western blot, qRT-PCR, and luciferase reporter assays.

Responsibilities:
  • Design and clone expression vectors and IVT donor plasmids to support research initiatives.
  • Execute DNA and mRNA transfections in mouse and human cell lines.
  • Assess nucleic acid expression through molecular methods like qPCR, reporter assays and Western blotting.
  • Maintenance of detailed electronic laboratory notebooks (ELN) and preparation of summary slides

Job Requirements


Requirements, Knowledge, Skills, and Abilities:
  • Education/Experience: Bachelor's degree with 5+ years or a Master's degree with 2+ years of experience in molecular biology, pharmaceutical sciences, or a related field.
  • Molecular Biology: Required proficiency in advanced cloning (Gibson assembly, Golden Gate, site-directed mutagenesis) and IVT.
  • Functional Assays: Hands-on expertise in measuring transgene delivery success via reporter assays and qRT-PCR.
  • Cell Culture: Preferred experience in genetic manipulation of cell lines and primary cells (e.g., T cells, monocytes, hepatocytes).
  • Software/Tools: Desired proficiency in Snapgene, Prism, and MS Office.

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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