Research Associate II

South San Francisco, CA 94080

Posted: 01/12/2021 Employment Type: Contract Industry: Research - Discovery Job Number: 8489

Job Description

Our client is a leading biotechnology company that discovers, develops, manufactures, and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world' s leading biotech companies, with multiple products on the market and a promising development pipeline.



We are looking for a team player to join Structural Biology Department’ s Discovery Proteins group supporting ongoing research projects. The successful candidate will work on the purification and characterization of recombinant proteins produced in mammalian, insect and bacterial cells.


Job Requirements


  • Experience with column chromatography techniques such as affinity, ion exchange, size exclusion chromatography and reversed-phase HPLC on automated AKTA liquid chromatography systems to produce high quality recombinant proteins and analytical HPLCs for protein characterization.
  • Proficient in protein conjugation techniques such as biotinylation and fluorescent labeling of proteins, cleavage of purification tags and removal of endotoxin from protein preps. 
  • Skilled in protein characterization techniques including SDS-PAGE gels, mass spectrometry, multi-angle light scattering (SEC-MALS) and differential scanning fluorimetry (DLS).
  • Sample management to support and organize inventory of recombinant proteins.
  • Strong organizational, communication, interpersonal skills, team-oriented, dependable, and self-starter.
  • Ability to follow detailed verbal and written instruction.
  • Able to apply analytical skills and judgment in assessing the quality of data.
  • Must be self-motivated, able to multi-task, and meet timelines efficiently and productively.



The successful candidate must have either a BS/MS degree with ~3-5 years of experience or a PhD with 0-2 years of experience in Biochemistry, Molecular Biology, Protein Chemistry, Structural Biology or a related discipline.

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