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Research Associate II/III

South San Francisco, CA 94080

Posted: 06/13/2024 Employment Type: Contract Industry: Research and Discovery Job Number: 11742 Pay Rate: $39.00 - $72.00 Remote Friendly: Onsite

Job Description

Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world's leading biotech companies, with multiple products on the market and a promising development pipeline.

The Position:

Our client's Preclinical and Translational PKPD (PTPK) Department is looking for an exceptional laboratory-based contract scientist to work in the investigative PK/ADME group in South San Francisco. This position is to investigate the pharmacokinetics, biodistribution, metabolism, and the PKPD relationships of novel therapeutics in preclinical setting in support of early and late stage drug development. The candidate will be responsible for designing and implementing in-vitro and in-vivo studies that includes cell based in-vitro assay, radiolabeled tissue distribution studies, ADME studies to understand the properties of protein and nucleotide therapeutics. The candidate will interact and develop close partnerships across various functions including Research, Safety Assessment, PD Biomarker, Bioanalytical Assays, Clinical Sciences, Formulation and Regulatory. Additional component of the job will be sample/data analysis and presentation of results to cross-functional teams, department meetings, review committees, internal/external conferences, and regulatory agencies.

Job Responsibilities:
  • Design and implement in-vitro and in-vivo studies to address ADME questions of protein and nucleotide therapeutic. Writing and submitting protocol to cross functional team for review.
  • Carry out sample analysis (including tissue processing) by using different analytical methods.
  • Characterize and identify possible biotransformation products from protein and nucleotide therapeutic in different biological matrices.
  • Interpret data and communicate results in department meeting and project team meeting.
  • Prepare presentation and report for conferences, manuscripts and regulatory documents.

Job Requirements

Who you are:
  • Candidate should be highly motivated individual with a passion for science, a curiosity of solving complex problem, attention to detail, as well as demonstrated effectiveness to work independently and in team settings.
  • The candidate should also be proficient in a broad variety of lab related technical skills (cell culturing, cell base assay, analytical chemistry, etc.).
  • You are expected to have some knowledge in basic pharmacology, drug metabolism (characterizing and identifying metabolite) and in PKPD relationship.
  • An individual with strong communication and collaboration skill, along with the ability to clearly articulate solution.

Education and experience:
  • A Bachelors or Masters degree in Biology or Biochemistry with 0-3 years in the Research and Development experience.
  • Must have demonstrated a general working knowledge of cell based assay, analytical techniques (HPLC, LSC, mass spectrometry and etc.), and laboratory skills.
  • Understanding of PK concepts and the use of novel drug delivery system is preferred.
  • Previous experience in chemistry, especially with working with radio-isotope, is a plus.
  • Good oral and written communication skills are important as well as demonstrated effectiveness in working independently and in a team setting.

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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About South San Francisco, CA

Ready to take the next step in your career journey? Explore our job opportunities in the vibrant area surrounding South San Francisco, California! Known for its proximity to the iconic Golden Gate Bridge and the bustling tech hub of Silicon Valley, this region offers unrivaled growth potential and a dynamic work environment. With a unique blend of culture, including the renowned SFMOMA art museum, the lively Castro District, and delectable cuisine like the famous sourdough bread at Boudin Bakery, South San Francisco is the perfect place to thrive professionally while enjoying the beauty of nearby parks like Golden Gate Park and the breathtaking views of the Pacific Ocean. Join us in discovering the endless possibilities for your career in this enchanting region!