Research Associate I

South San Francisco, CA 94080

Posted: 06/21/2019 Employment Type: Contract Industry: Research - Discovery Job Number: 6440

Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world' s leading biotech companies, with multiple products on the market and a promising development pipeline.

 

Job Description Summary

We are looking for a highly motivated candidate to actively work in the lab in collaboration with other researchers in different projects. He/she must be experienced in cell culture and have skills in molecular biology. To support our Client’ s drug discovery programs, he/she will actively participate in the development of microfluidics platforms (MPS-3D), providing cells, treating and performing assays to access cytotoxicity and metabolic changes upon treatment. The ability to make detailed observations, analyze data, and interpret results is imperative. He/she is expected to contribute with scientific insights, be creative to troubleshoot, work independently and have great communication skills. The candidate may participate in scientific conferences, contribute to peer review publications and be responsible for identifying patentable inventions. May act as principal investigator in conducting own experiments.

 

Job Description

Our Client has an open Scientific Researcher/Senior Scientific Researcher position in the Investigative Toxicology group within the department of Safety Assessment located in their South San Francisco campus.  The Investigative Toxicology group’ s goal is to use ex vivo and in vitro tools to assess safety liabilities and mechanisms of toxicities observed pre-clinically to support the entire portfolio spanning discovery through development.  This laboratory-based role involves developing, qualifying, and implementing new assays and technologies to support the Investigative Toxicology group and overall Safety Assessment. 

 

Skills:

Successful candidates will provide scientific and technical support for platforms, assays, and programs developed or supported by the investigative toxicology group by:
  • Working independently or under the direct supervision of a Scientist to perform or support non-GLP laboratory experiments, including model development, routine toxicity screening, and mechanism of toxicity, with minimal direct supervision.
  • Performing applicable techniques (primary cell culture, flow cytometry, gene expression analysis, cell viability, high content screening, etc.) are required.
  • Maintaining documentation related to protocol execution.
  • Writing pre-clinical protocols and contributing to final reports as appropriate.
  • Adhering to departmental SOPs to ensure study integrity and quality.
  • A high level of independent work specifically with regards to method and model development.
  • The ability to independently perform all methods and conduct all study types commonly employed by the team.
  • Presenting data at project team, department, and outside meetings as appropriate.

 

Education:
  • Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required; Masters (MS) degree is desirable, but not required.

 

Technical Experience Requirements:
  • 2-3+ years of experience with hypothesis-driven research and conduct of experiments to address is required.
  • Ability to independently design and conduct research to address such questions is required.
  • Ability to analyze, integrate, and present all data in a presentation is required.
  • Must be able to present data and associated materials to project teams or at other forums
  • Experience with molecular biology techniques and next-generation sequencing is highly desired

 

Role will involve:
  • Sitting or standing for extended periods.
  • Performing repetitive tasks such as cell culture, pipetting and labeling tubes.

 

Skills:

Successful candidates will provide scientific and technical support for platforms, assays, and programs developed or supported by the investigative toxicology group by:

  • Working independently or under the direct supervision of a Scientist to perform or support non-GLP laboratory experiments, including model development, routine toxicity screening, and mechanism of toxicity, with minimal direct supervision.
  • Performing applicable techniques (primary cell culture, flow cytometry, gene expression analysis, cell viability, high content screening, etc.) are required.
  • Maintaining documentation related to protocol execution.
  • Writing pre-clinical protocols and contributing to final reports as appropriate.
  • Adhering to departmental SOPs to ensure study integrity and quality.
  • A high level of independent work specifically with regards to method and model development.
  • The ability to independently perform all methods and conduct all study types commonly employed by the team.
  • Presenting data at project team, department, and outside meetings as appropriate.

 

Education:

  • Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required; Masters (MS) degree is desirable, but not required.

 

Technical Experience Requirements:

  • 2-3+ years of experience with hypothesis-driven research and conduct of experiments to address is required.
  • Ability to independently design and conduct research to address such questions is required.
  • Ability to analyze, integrate, and present all data in a presentation is required.
  • Must be able to present data and associated materials to project teams or at other forums
  • Experience with molecular biology techniques and next-generation sequencing is highly desired

 

Role will involve:

  • Sitting or standing for extended periods.
  • Performing repetitive tasks such as cell culture, pipetting and labeling tubes.
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