Research Associate I

South San Francisco, CA 94080

Posted: 08/21/2018 Employment Type: Contract Industry: Research - Discovery Job Number: 4681

Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world' s leading biotech companies, with multiple products on the market and a promising development pipeline.

 

Duties:
  • Performs research and/or development in collaboration with others for projects. In particular, a focus of this position will be performing cell cultivation to identify suitable lots of primary human hepatocytes for regularly-performed cytotoxicity assays, and establishing 3-demensional spheroids for supporting our drug discovery programs.
  • Makes detailed observations, analyzes data and interprets results.
  • Investigates, creates and develops new methods and technologies for project advancement.
  • Maintains high level of professional expertise through familiarity with scientific literature.
  • May participate in scientific conferences and contribute to scientific journals.
  • May be responsible for identifying patentable inventions.
  • May act as principal investigator in conducting own experiments.

 

Skills:
  • Successful candidates will provide scientific and technical support for platforms, assays, and programs developed or supported by the investigative toxicology group by:
  • Working independently or under the direct supervision of a Scientist to perform or support non-GLP laboratory experiments, including model development, routine toxicity screening, and mechanism of toxicity, with minimal direct supervision
  • Performing applicable techniques (primary cell culture, flow cytometry, gene expression analysis, cell viability, high content screening, etc.) as required.
  • Maintaining documentation related to protocol execution.
  • Writing pre-clinical protocols and contributing to final reports as appropriate.
  • Adhering to departmental SOPs to ensure study integrity and quality.
  • A high level of independent work specifically with regards to method and model development.
  • The ability to independently perform all methods and conduct all study types commonly employed by the team.
  • Presenting data at project team, department, and outside meetings as appropriate.

 

 

Education:

  • Bachelors (BS/BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required; Masters (MS) degree is desirable, but not required.

Technical Experience Requirements:

  • 2-3+ years of experience with hypothesis-driven research and conduct of experiments to address is required.
  • Ability to independently design and conduct research to address such questions is required.
  • Ability to analyze, integrate, and present all data in a presentation is required.
  • Must be able to present data and associated materials to project teams or at other forums
  • Experience with molecular biology techniques and next-generation sequencing is highly desired
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