Research Associate I

South San Francisco, CA 94080 | Contract

Post Date: 07/27/2018 Job ID: 4548 Industry: Research - Discovery

Our client is a leading biotechnology company that discovers, develops, manufactures and commercializes medicines to treat patients with serious or life-threatening medical conditions. They are among the world' s leading biotech companies, with multiple products on the market and a promising development pipeline.

 

Duties:
  • We have an opening for a talented Scientific Researcher/Senior Scientific Researcher to join our Biochemical and Cellular Pharmacology Department.
  • The successful candidate will be responsible for supporting biochemical and cellular characterization of protein therapeutics for immuno-oncology.
  • More specifically, the individual will develop, validate and execute biochemical and cell-based assays to characterize and screen biologic therapeutics in vitro and ex vivo, to support lead-finding/optimization efforts.
  • Responsibilities include developing and implementing pharmacokinetic/pharmacodynamic assays and quantitating biomarkers.
  • In addition, the candidate will function as part of a multi-disciplinary project team that will coordinate with Cancer Immunology, Protein Chemistry, Antibody Engineering, and Translational Oncology groups to advance lead molecules of the projects.

 

 

Skills:

  • Practical experience in the design, development, validation and execution of biochemical and cell-based assays to characterize protein therapeutics is required.
  • Experience with multi-color flow cytometry, T cell functional assays, ELISA assays, culture of mammalian cell lines and primary immune cells is required.
  • Experience with dendritic cell differentiation and culture is a plus.
  • Experience with microscopy and/or high content image analysis is a plus.
  • Familiarity with automated or semi-automated instrumentation, while not required, would be advantageous, as would familiarity with the multi-disciplinary activities of antibody lead profiling.
  • Excellent teamwork, communication, time management, and organization skills.

 

Education:

  • The qualified individual will possess a B.S. or M.S. degree in Immunology, Biochemistry, Cell Biology, or a related field with relevant immunology/immuno-oncology experience in academia, biotechnology and/or pharmaceutical industry.
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