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Research Associate/Associate Scientist, Disease Modeling

South San Francisco, CA 94080

Posted: 12/12/2022 Employment Type: Direct Hire Industry: Research and Discovery Job Number: 10507 Pay Rate: $75k - $80k

Job Description


Our client is an early-stage biotechnology company developing a novel technology platform that can provide safe and persistent control of targeted gene regulation.

 

Duties:
  • Responsible for developing and executing novel protocols for cellular disease modeling in Therapeutic Team.
  • This individual will perform cell line engineering and build an extensive repertoire of scalable cellular models for multiple disease indications.
  • This position includes technically diverse bench work and the training of research staff in techniques and equipment used to support high throughput iPSC differentiation and target validation.
  • iPSCs cell line engineering.
  • Design and perform in vitro and ex-vivo experiments for cellular disease modeling.
  • Support the development of assay strategies and work across functions in experimental design, troubleshooting, sample analysis, data interpretation, and report generation.
  • Perform assay such as but not limited to immunocytochemistry, flow cytometry, RT-qPCR.
  • Develop, author, and maintain SOPs/ELN.
  • Daily management of the iPSC culture as needed.

 

Job Requirements


Required Skills:
  • Must have iPS cell experience, as well as technical experience with primary cell culture and cell culture of immortalized cell lines.
  • Experience with cell line engineering (using CRISPR).
  • Ideal candidates will have a depth of research experience in cell and molecular biology and assay development.
  • Strong skills in molecular biology (including DNA and RNA extraction, PCR, qPCR).
  • Familiar with molecular cloning, gene engineering, and seamless cloning.

 

Preferred Skills:
  • Both 2D and 3D (organoid) cell culture and assay experience.
  • Experience in characterizing cellular phenotype via FACS, transcriptomics, or high-content imaging.
  • Experience with lab automation for the cell-based screening assay.
  • Experience with coding (R, Python).

 

Education:

Associate Scientist:
  • BS + >5 years or MS + >3 years’ experience in an academic or industrial setting.

Research Associate:
  • BS + > 1-2 years or MS + 0-1 year experience in an academic or industrial setting.

Meet Your Recruiter

Jay Hite
Recruiter, Account Manager

As a Recruiter at Compass, Jay enjoys meeting job seekers and helping them to find new and exciting opportunities. He enjoys the process of getting to know candidates and learning all about their experience and what their future goals are. Jay feels the excitement of his candidates and is passionate about helping to find a fit both culturally and professionally. 

When Jay isn’t working, he enjoys bike rides, trying out new foods, tequila tasting and watching movies.  

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